Yellow Fever

Yellow Fever vaccination can be given to persons aged 60 years and over but they should make an informed decision based on the following.

In general, all persons who are travelling to yellow fever endemic regions should be offered yellow fever vaccination unless there are medical contraindications.

Yellow fever endemic regions are where yellow fever cases in humans are occurring or where there is the potential for human infection because of the presence of the mosquito vector or the virus in non-human primates. For details of the risk of yellow fever in differing regions/ countries visit www.fitfortravel.nhs.uk

Serious adverse effects from the yellow fever vaccine are rare. Nevertheless, vaccine-associated viscerotropic disease (affecting the internal organs) occurs in 0.4 cases of every 100,000 yellow fever doses given. Neurological diseases (affecting the brain) occur in 0.8 cases of every 100,000 doses.

Individuals who are aged 60 years and over appear to be at increased risk of 2 cases in every 100,000 doses given. To date, these reactions have only occurred in persons receiving yellow fever vaccine for the first time.

It is for the individual to consider for themselves the risk of the adverse effects from the vaccine against the risk of yellow fever or whether to change their planned itinerary in order to avoid any risk at all.